Organosulfur Compounds
TARGETMOL CHEMICALS INC TETRABENAZINE METABOLITE 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Tetrabenazine Metabolite ((-)-(beta)-HTBZ) a vesicles monoamine transporter 2 (VMAT2) inhibitor is an active metabolite of Tetrabenazine. Tetrabenazine Metabolite has a high affinity for VMAT2 with a Ki of 13.4 nM. Tetrabenazine Metabolite is often used to study chorea associated with Huntington's disease and other hyperactivity disorders. purity: 95%
Medchemexpress LLC Sulforaphane | 4478-93-7 | MFCD00198068 | 98.9% | 177.29 g/mol | C6H11NOS2 | 5 MG
Sulforaphane is a research-grade isothiocyanate that activates the Keap1/Nrf2/ARE antioxidant pathway and inhibits histone deacetylases. Supplied as a high-purity powder, it is intended for use in in vitro and in vivo studies of antioxidant response, anticancer activity, and anti-inflammatory mechanisms.
- High purity: 98.9%.
- CAS number: 4478-93-7.
- Molecular formula: C6H11NOS2; MW: 177.29 g/mol.
- Suitable for in vitro and in vivo applications.
- Storage: powder -20°C; in solvent -80°C for long-term storage.
- Available in small research quantities, including 5 mg.
Medchemexpress LLC Sulforaphane | 4478-93-7 | 99.0% | 177.29 | 500 MG
Sulforaphane is an orally active inducer of the Keap1/Nrf2/ARE pathway. It promotes the transcription of tumor-suppressing proteins and effectively inhibits the activity of HDACs. By activating the Keap1/Nrf2/ARE pathway and further inducing HO-1 expression, Sulforaphane protects the heart. It suppresses high glucose-induced pancreatic cancer through AMPK-dependent signal transmission and exhibits both anticancer and anti-inflammatory properties.
- Orally active inducer of the Keap1/Nrf2/ARE pathway.
- Promotes transcription of tumor-suppressing proteins.
- Effectively inhibits HDACs activity.
- Protects the heart.
- Suppresses high glucose-induced pancreatic cancer.
- Exhibits anticancer and anti-inflammatory properties.
- Induces cell cycle arrest and apoptosis.
- Reduces ROS production and cell apoptosis.
eMolecules 67-68-5 | Dimethyl sulfoxide | Combi-Blocks, Inc. | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 500g | 642100602
Dimethyl sulfoxide | Combi-Blocks, Inc. | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 95.000 | CS(C)=O | 500g | 642100602
Medchemexpress LLC N'-(3-acetylphenyl)-N-(3-(2-methoxyethyl)-2,4-dioxo-1-(2-(piperidin-1-yl)ethyl)-1,2,3,4-tetrahydroquinazolin | 2946701-09-1 | 99.3% | 507.58 g/mol | C27H33N5O5 | 10 MG
COP1-ATGL modulator 1 is an orally active small-molecule research reagent that modulates the COP1-ATGL pathway. It increases ATGL protein expression, reduces ATGL and COP1 ubiquitination, and diminishes lipid accumulation in hepatocytes at nanomolar concentrations. Supplied as a white to off-white solid with high purity and defined storage recommendations for powder and solution.
- Orally active modulator of COP1-ATGL signaling.
- Increases ATGL protein expression at nanomolar concentrations.
- Reduces ATGL and COP1 ubiquitination in cellular assays.
- High purity suitable for research applications.
- Stable solid with recommended low-temperature storage.
Medchemexpress LLC GLP-1R modulator C16 | 875005-43-9 | 98.7% | C21H26ClFN2O3 | 10MM/1ML
GLP-1R modulator C16 is an allosteric modulator that enhances GLP-1 binding to GLP-1R via a transmembrane site.
- Enhances GLP-1 binding to GLP-1R
- Operates via a transmembrane site
- Purity of 98.7%
Medchemexpress LLC CXCR7 modulator 2 | 2227426-37-9 | 98.71% | 522.68 | 1 ML
CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. It is for research use only and not sold to patients. This modulator offers protection against cardiac injury.
- Potent CXCR7-binding affinity (Ki=13 nM).
- β-arrestin activity (EC50=11 nM).
- Improved selectivity in the GPCR panel.
- Improved therapeutic index in the hERG patch-clamp assay.
- Moderate to high in vitro turnover in NADPH-supplemented mouse-liver microsomes (MLM, 93 μL/min/mg) and hepatocytes (28 μL/min per million cells).
- Good aqueous solubility.
- Rapidly absorbed with a mean maximal plasma concentration (Cmax) of 682 ng/mL at 0.25 h (Tmax).
- Reduces cardiac fibrosis in an isoproterenol-induced cardiac injury model in mice.
Aobchem (2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g
(2-Bromophenyl)(isopropyl)sulfane | ≥97% | CAS 245739-32-6 | C9H11BrS | 1g